Advanced Bloodwork

Advanced bloodwork at Archetype is a curated panel that captures cardiovascular, metabolic, inflammatory, hormonal, hepatic, renal, and nutritional health — far broader than the lipid panel and basic chemistry that define a standard physical.

We don't run every test that exists. We run the tests that change clinical decisions. Each marker on the panel earns its place because it answers a specific question, predicts a specific outcome, or guides a specific intervention.

Most patients have a single morning blood draw, fasted, with results back within several days for review.

A standard annual physical typically includes a lipid panel, a basic metabolic panel, and a CBC. That's enough to detect overt disease — but it misses most of the early signals that predict it.

Markers like apoB, Lp(a), insulin, fasting and post-prandial glucose patterns, hsCRP, homocysteine, ferritin, and a properly interpreted thyroid panel routinely identify risks that wouldn't surface in a standard workup. Catching them in your 30s, 40s, or 50s gives you decades of runway to do something about it.

Just as importantly, we interpret the results in context — not against the broad reference ranges that include most of the unhealthy adult population, but against ranges that reflect actual optimal physiology.

• Cardiovascular: apoB, Lp(a), full lipid panel, hsCRP, homocysteine
• Metabolic: fasting glucose, fasting insulin, HOMA-IR, HbA1c, uric acid
• Hepatic and renal: full liver panel including GGT, kidney function, electrolytes
• Hormonal screening: thyroid (TSH, free T4, free T3), DHEA-S, cortisol when indicated
• Nutritional: vitamin D, B12, folate, ferritin, magnesium, omega-3 index
• Hematologic: complete blood count with differential

• Anyone whose annual labs come back 'normal' but who suspects something more useful could be measured.
• Patients with a family history of cardiovascular disease, diabetes, autoimmune disease, or cancer.
• Anyone who wants a real baseline against which to measure changes from training, nutrition, or therapy.
• Patients on medications who want a careful look at how those medications are affecting metabolism, lipids, or inflammation.

• A single morning blood draw, fasted (water and medications as usual unless directed otherwise).
• We sit down to walk through every meaningful result in plain language, in the context of the rest of your evaluation.
• You leave with a written summary of your priorities, the lifestyle and clinical interventions that target each one, and a re-test cadence for the markers that matter most.

We don't read your labs in isolation. Each marker is interpreted alongside your CAC score, body composition, fitness, sleep, family history, and personal goals.

Reference ranges are starting points, not goals. We're focused on optimal ranges supported by outcome data — which often differ meaningfully from the broader reference intervals printed on the report.

The most important markers are usually re-checked every 6 to 12 months while we make changes, then less frequently once stable. Less critical markers may only need annual or every-other-year tracking.

1. Sniderman AD, Thanassoulis G, Glavinovic T, et al. Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review. JAMA Cardiol. 2019;4(12):1287-1295.
2. Epstein E, et al. Apolipoprotein B outperforms low density lipoprotein particle number as a marker of cardiovascular risk in the UK Biobank. Eur J Prev Cardiol. 2025.41,099 patients with 10+ years of follow-up — cardiovascular risk was already elevated at just 2% ApoB/LDL-particle discordance.